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Machu Picchu and the surrounding ruins are the star attraction in this Andean region. Quaint Machu Picchu Pueblo, located at the base of the mountain, is the nearest town – after that, the second most popular gateway city is Cusco, located 74 miles to the southeast. Although it’s far, many people do choose to stay in Cusco and make the 4-hour train ride to the Incan city for either a day trip or, preferably, a long weekend.