Great River Road

The Great River Road follows the course of the Mississippi River through 10 states – from northern Minnesota to Louisiana – on 2,000-mile-plus route that takes most travelers up to 10 days to complete. (Plan your road trip or find itineraries here.) Possible stops include the Mark Twain Museum Interpretive Center in Hannibal, Missouri; The Gateway Arch in St. Louis; the Delta Blues Museum in Clarksdale, Mississippi; and Vicksburg National Military Park.

Read more: 13 Ways to Experience Louisiana Like a Local