Near Fairhope, in the beach community of Point Clear, the Grand Hotel Golf Resort and Spa has two golf courses, a 20,000-square-foot-spa, and direct access to the beach. Its restaurant, Southern Roots, focuses on farm-to-table cuisine. The resort’s grounds are trimmed with massive oak trees that will make you feel like you’ve landed in a fairytale.

Alaska is known for its rugged terrain and beautiful landscapes. The Alyeska Resort near Anchorage is a four-season destination with day trips to the Kenai Peninsula in the summer and northern lights viewings in winter. Its five restaurants range from Pan-Asian cuisine to bar grub. After a day of skiing or mountain biking, hit the spa, which looks out to the Alaskan wilderness. 

Set in the foothills of the Bradshaw Mountains, Castle Hot Springs draws visitors from far and wide. The three natural pools, which remain a toasty 115 degrees year-round, are used to heat the main resort pool. The all-inclusive resort boasts farm-to-table meals. Farm tours offer patrons a glimpse of where the items on their plates are grown. The resort also has guided hikes and archery. 

The draw at Mountain Harbor Resort and Spa, on the shores of Lake Ouachita, is its collection of lake-front cabins equipped with full kitchens and comfortable living spaces. To truly unwind, book a treatment at Turtle Cove spa, an outdoor nature spa, where you’ll reconnect with lush surroundings while being pampered. 

Just north of the Santa Monica pier, the striking Fairmont Miramar Hotel and Bungalows was built to be a private residence back in 1921. While staying here, you’ll enjoy manicured gardens, poolside accommodations, and sweeping ocean views. The resort recently redesigned its lobby lounge and library with a bit of old Hollywood glamour and a new gin program and bar cart service. Its restaurant, FIG, features farm-to-table fare with a seasonal menu.

Viceroy Snowmass is known as one of the best mountain resorts in Colorado. The resort features a fantastic spa, a trail-side bar where you can grab a beer or cocktail after a hike, and chalet rooms with ultra-luxe amenities. During the summer months, the resort offers everything from private helicopter tours of the mountains to wine tours. While winter brings activities like dog sledding and an alpine coaster. 

In the Litchfield Hills of Connecticut, the AAA Five Diamond Winvian Farms resort comprises 18 uniquely designed private cottages nestled among 113 acres of meadows. The restaurant has a seasonal menu with produce from the on-site green houses. The 5000-square-foot spa is one of the only spas in New England that features Biologique Recherche custom facials. 

The historic Bellmoor Inn and Spa in Rehoboth Beach is two blocks from the shore and around the corner from great shopping, dining, and nightlife. The resort has 56 rooms and 26 suites with personalized service. Each morning, there’s a spread of coffee and pastries, along with hot items cooked to order. When it’s time to hit the beach, reserve a chair and umbrella at the hotel, then take the complimentary shuttle straight to the sand.  

Away from the hustle and bustle of the theme parks, the Ritz-Carlton Orlando offers unparalleled and personalized service for each guest. The glittering pool has a dedicated service team that will bring food and drinks right to your lounge chair. Don’t miss the restaurants, particularly Knife and Spoon from award-winning chef John Tesar. 

Sea Island, off Georgia’s southeastern coast, is a private-island escape with five miles of private beach to bask in the summer sun. Guests can rent bikes or golf carts to explore the island, or enjoy excursions like a sea turtle patrol with a naturalist, salt marsh kayaking, or golf at one of three championship golf courses. 

The Four Seasons Maui at Wailea is known for its commitment to working in harmony with the local landscape and community. The resort has one of the top-rated spas in the United States, where you can enjoy a massage in a beachside, open-air hut. It is also home to three of the state’s most critically acclaimed restaurants, including one by Wolfgang Puck.  

Perched at 5,000 feet above sea level, Shore Lodge has direct access to Payette Lake, where visitors can partake in water sports and swimming. The resort’s private movie theater hosts screenings for guests and private groups. During the winter months, you can rent snowshoes to explore the outdoors with a guide or on your own as well.

At the Langham Chicago Hotel, you’ll wake up to views of the cityscape, the Chicago River, and beautiful Lake Michigan. The resort has 268 guest rooms and 48 suites, all designed with the luxury traveler in mind, including an all-marble bathroom. Don’t miss the famous afternoon tea—a Langham tradition carried over from its original hotel in London—where you can indulge in sweet and savory treats along with teas of your choice.  

In Carmel City, Hotel Carmichael boasts 122 rooms and suites heavily influenced by the local art scene. The halls and common areas are adorned with works inspired by the art and music culture. For dining, Vivante French Eatery makes delectable but approachable French fare for hungry visitors. 

The Hotel Julien Dubuque is located in the heart of downtown Dubuque, Iowa. The resort has 133 rooms including a suite themed to notorious mobster Al Capone. Caroline’s Restaurant serves seasonal American eats for breakfast, lunch, and dinner. The hotel has partnered with local purveyors to grow and harvest produce specifically for the restaurant too.

Kansas may not be known for luxury resorts, but Anderson Bed and Breakfast in Manhattan is worth the splurge. The bed and breakfast occupies a Craftsman-style home from 1910 just a short walk from Kansas State University. When you stay in one of the three guest rooms, you’ll be treated to homemade breakfast with eggs from chickens in the backyard. 

One of the more recent hotel openings in Louisville is The Grady Hotel, located in the heart of the Market District downtown. The historic building was built in 1883 and was once a medicinal bourbon apothecary. Its restaurant, The Wild Swann, also has a story: It was named after the Swann-Abram Hat Company, which made derby hats in the same building in the 1920s. The restaurant specializes in small, shareable dishes and craft cocktails that go down a little too easy.

Southern hospitality is on full display at Maison de la Luz in New Orleans. The hotel features 67 charming guest rooms and suites that instantly feel like home. The hotel has a secret entrance into Bar Marilou, a cozy spot with a hotel-guests-only nook. When you’re ready for live music, head over to Three Keys, where Maison de la Luz guests get priority reservations. 

Kennebunkport is home to Hidden Pond, an enclave of private cottages, bungalows, and treetop lodges. Guests can explore nearby hiking trails, forest bathing, biking, floral arranging classes, and more. The farm-to-fork restaurant Earth uses all seasonal and organic ingredients in dishes that can be enjoyed in the main dining room or at a private table in the garden shed. 

Baltimore is known for views of the bay and a stellar food scene. The Four Seasons Hotel Baltimore combines the best of both. The resort has a rooftop pool that overlooks the harbor, an idyllic spot for a sunset drink. If you're looking to stay fit while on vacation, consider the resort’s Peloton on-the-go service, where the hotel will deliver a Peloton bike to your room for private use.

The Langham, Boston has undergone a major $200 million renovation. The hotel’s new digs include an art collection that pays tribute to the history and culture of Boston. Each of the beautifully refurbished guest rooms show off classic New England style with a blue-and-grey color scheme and stunning views of the city. 

Since 1887, the Grand Hotel on Mackinac Island has been one of the top summer destinations in America. Open only from May through October and accessible via ferry or plane, the island is a true summer respite. Hotel guests can enjoy lawn games on the Tea Garden, a swim in the pool, and kick-back on the world’s largest front porch. Before checking out, stop by Sadie’s Ice Cream Parlor, a local favorite with two-dozen artisanal flavors. 

Hotel Ivy in downtown Minneapolis features stunning common spaces and plush rooms that put you at ease from the moment you walk in. The Hotel Ivy bar serves rare Champagne and sophisticated cocktails (let one of the mixologists choose for you). The spa recently went through a major refurbishment and is designed around crystal-based healing practices. 

The Fairview Inn is a boutique hotel that’s hosted in a historic 1908 Colonial Revival mansion. Each of the rooms and suites are decorated with southern-style furniture and all of the amenities of modern day living. The Library Lounge has daily dinner and drinks specials, and 1908 Provisions is one of the top farm-to-table restaurants in Jackson. 

The Four Seasons Hotel St. Louis is located steps away from the Gateway Arch in downtown with views of the mighty Mississippi River. The hotel is known for its massive Sky Terrace, which has a heated pool and private cabanas. Have a meal with family or friends at Cinder House, where the menu is filled with shareable plates and drinks with a South American twist. 

In the unspoiled Bitterroot Valley, Triple Creek Ranch offers all-inclusive outdoor experiences like mountain biking, fly fishing, and snowshoeing. Each of the cabins come with a wood-burning fireplace, a hot tub, and original artwork of the American west. When it’s time for dinner, head to the restaurant for a taste of the property’s garden. 

The Magnolia Omaha occupies the former Aquila Court Building, built in 1923. The location couldn’t be better: In the middle of Omaha’s arts and entertainment district, and within walking distance of the Orpheum Theatre and the Holland Performing Arts Center. Each guest room is well-sized and appointed, with plush bedding and cozy chairs where you can unwind after a long day. 

Though it’s right on the Las Vegas strip, the Waldorf Astoria Las Vegas manages to create an environment where guests can relax without the hundreds of extra people at the casino. A sky bridge connects the hotel to The Shop at Crystals. Relax at one of three pools and an award-winning spa.

The Omni Mount Washington Resort—with its stunning Spanish Renaissance architecture and breathtaking views of the White Mountains—has been favored among celebrities and presidents for decades. Guests can do everything from alpine skiing to canopy tours via zip line. The onsite golf course was designed by famed designer Donald Ross. The spa offers views of Mount Washington, the Presidential Range, and Crawford Notch, which should help you to relax before your treatment. 

On the lively Pier Village boardwalk in Long Branch, the new Wave Resort has 67 rooms and suites with oceanfront views and a walkout terrace. When the beach is too crowded, head to the pool, which overlooks the Atlantic Ocean and has a swim-up bar. As night falls, there's The Patio, styled after a VIP lounge with craft cocktails and dining. 

The Inn of the Five Graces in Santa Fe is set in an enclave of rehabbed adobe buildings.The resort offers 24 rooms and suites including a two-story 1,975-square-foot villa. When guests check-in, they are greeted with a local delicacy, along with snacks and refreshments in their room. After exploring the neighborhood, relax in the hotel's lush courtyard, where fountains and gardens make for a welcome oasis. 

The Baccarat Hotel New York is aptly designed to feature the famed French crystal manufacturer’s masterpieces. The resort is steps away from the famous shops on Fifth Avenue and across the street from the Museum of Modern Art. It has 114 guest rooms and suites that are as stunning as the common places at the hotel. When hunger strikes, consider going to one of the salon-inspired spaces, where you can enjoy bites created by a two Michelin-starred chef. As you explore the city, consider renting one of the luxury house cars, which you can take anywhere within 15 blocks of the hotel.

Set against the Blue Ridge Mountains in Asheville, The Foundry Hotel is housed in a restored steel factory. While there, take a neighborhood tour with a local historian or a brewery tour, which the hotel can drive you to and from via the resort’s Tesla Model X house car. If you have a large group of family and friends traveling together you can even rent out an entire building for a private experience. 

While North Dakota might not be top-of-mind for a luxury retreat, The Hotel Donaldson in Fargo is a worthwhile stop. The brick building that the hotel is located at was built in 1893. Each of the guest rooms is filled with art and most nights you can have a cocktail while listening to live music from local musicians. 

The Ritz-Carlton Cleveland, located downtown, has 206 guest rooms that were recently upgraded with an aesthetic inspired by the city’s steel-industry roots. The Club Lounge at the resort has stunning views of the city’s skyline. Guests can also enjoy TURN Bar and Kitchen, where the culinary team partners with local farmers and butchers to get prime ingredients.

The Colcord Hotel stands out among the Oklahoma City skyline: Built in 1910, it was the first skyscraper in Oklahoma City. The beautiful rooms are enhanced by the fantastic service, which includes coffee and tea delivered to your room each morning. There are two restaurants that serve seasonal American grub, with ingredients sourced from local purveyors. 

Tetherow Resort is set on 700 sprawling acres bordered by Bend City and Deschutes National Forest. The resort focuses on being environmentally friendly, while still providing luxury accommodations and service. There are 50 eco-friendly hotel rooms and private vacation home rentals, and guests can explore miles of trails on foot or on bike. The resort shuttle can take you to The Old Mill District and Silver Moon Brewing, as well as the airport. 

For those looking for a spa retreat, look no further than The Lodge at Woodloch. The spa resort is home to miles of trails, on which you can disconnect from your phone and reconnect with your loved ones or yourself. The spa offers a sleep-enhancing treatment that will leave you feeling well-rested and help you sleep better at home. When it’s actually time to lay down, guests can order a pillow from one of the eight on the pillow menu. 

The luxe, oceanfront Ocean House resort in Watch Hill has 49 guest rooms, 20 suites, and seven cottages. While on vacation here you can take part in activities like food foraging, art classes, croquet clinics, and private boat outings. If you’re looking for something a little slower paced, walk down to the private beach, then head to the Sipping Terrace for a gin cocktail to catch the setting sun.

In the heart of the low country, the Montage Palmetto Bluff is dripping with Spanish moss and southern hospitality. Guests can choose from a variety of accommodations, from rooms and suites, to entire homes and cottages. For fun, rent one of the poolside cabanas, cruise aboard a restored 1913 yacht, or bike to a shaded spot for a Champagne picnic packed by the resort. 

The Hotel Alex Johnson has been a South Dakota icon since 1928. The hotel is stunning, but it’s also rumored to be haunted (a draw from some visitors). The 143-room property displays a vast array of Native American art and decor. The rooftop Vertex Rapid City Sky Bar has a panoramic view of the city along with delightful craft cocktails and meals. 

The Joseph in downtown Nashville is known for its art collection, which comprises more than 1,000 pieces. Each of the 297 suites and guest rooms has its own curated selection, and the minibars include snacks and drinks from Nashville purveyors. When it’s time to rejuvenate, head to the rooftop spa for a foot scrub and soak in a copper tub before a treatment.

Hotel Crescent Court is located in the heart of Uptown Dallas, steps away from the nation’s largest arts district. The resort recently completed a $30 million refurbishment, including all 186 guest rooms and 40 suites. They say everything is bigger in Texas, so naturally there are 13 restaurants on site, including the high-end Japanese eatery Nobu, and a beautiful glass room called The Conservatory that serves breakfast and lunch. Head to the rooftop pool for views across the city.

The Amangiri in Canyon Point sits among 600 acres of protected land, perfect for travelers looking to explore the surrounding desert by hiking, on horseback, or by helicopter. The hotel has 34 suites, each of which has a private balcony, fireplace, and courtyard entrance. The restaurant supports the local Native American community by sourcing ingredients from the nearby co-ops. 

Barnard Vermont is home to Twin Farms, an exclusive mountain retreat known for its spa. The adults-only resort has 20 different accommodations that range from Moroccan-inspired to dog-themed. While there, take part in activities like a honey bee tour, fly fishing, and croquet. 

The Omni Homestead Resort, located in the foothills of the Blue Ridge Mountains, has hosted presidents dating back to Thomas Jefferson who came to experience its famed hot springs mineral waters. The resort is located on more than 2,000 acres and has endless activities, including two golf courses, carriage rides, and a falconry class.

The Four Seasons Hotel Seattle is located a short walk from the famous Pike Place Market. The property has 147 guest rooms and suites with views of Elliott Bay and downtown Seattle. It’s home to the largest collection of original artwork of the Pacific Northwest, which you’ll see on display in the lobby, spa, restaurants, and guest rooms. Each booking includes a coffee concierge and a Tesla house car for driving to nearby attractions. 

The Greenbrier in White Sulphur Springs is known for its laid back atmosphere and mountain views. The resort is a National Historic Landmark and has been welcoming guests since 1778. History buffs will enjoy learning that 27 of 45 American Presidents have vacationed here. It has a whopping 710 rooms, including 33 suites and 96 guest and estate homes. 

The American Club Resort, about an hour from Milwaukee in Kohler, was built in 1918 as a dorm for single, male immigrants of the factory. The campus was converted in 1981 to the resort, though it retained it’s whimsical storybook feel. It is known for its Eau de Vie Suite, where the bathroom has a sõk overflowing bath with chromotherapy, two powder rooms, and a glass fireplace. 

The Lodge and Spa at Brush Creek Ranch encompasses some 30,000 acres, a sporting and outdoorsman’s paradise. Resort activities include meeting its herd of goats, and learning about the art of cheesemaking. Guests can choose to stay in the main lodge or in a cabin suite or residence for a more private trip away from home.