Big Sur
Photo: Big Sur / iStock / Serbek

7. Pacific Coast out of San Diego

Hop on a cruise that explores the scenic coastal regions of California, the Pacific Northwest, and British Columbia, Canada. This is also an excellent way for wine enthusiasts to enjoy tours and tastings in regions that are world-famous for their vineyards.

Who Goes There? Holland America, Celebrity, and Crystal offer several sailings from San Diego that visit destinations including Monterey, Santa Barbara, Catalina Island, Seattle, Victoria, and Vancouver.